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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e44e58844a801533524d99e6c0790f00216adc32a8b0237829a80b1bb8e75d0' 
  AND token = 'p8ZacHipd/3wc5HLby1QTYWU33rbRhnuPT1/voDJhKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}