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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3ded01f675296f0c365a64a808b8421774067d5f9cd9b1aedfa96325ed443c' 
  AND token = '7QhtgE7VnIFGGYiZA1/80Rvf5xAX/tPYwX5Ra0mc0F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}