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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73134f5957afdd38d3a50d3a5d8c1b3321141e470078d6d81ad709011b943f0' 
  AND token = 'fQ0K1584AfvYbziz15iOEdAvFhluZYSeRObGazMYsgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}