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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f07d0552fa782b23ca0318812340dbc335fcb4182e16ac31b91d9128dd5a49f2' 
  AND token = 'tqp3fc/x2B7KlDH4A1WIEmebsQuR1b8H7is0DUyA8Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}