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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4455b0ebe571766452a53b295573b39e0a2bcf737637074858abc59a1bef4feb' 
  AND token = 'ocKNwe/NsxmvmNPsCffJzp56dDdwWtR2AYhYuGOzJ0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}