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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43eb7b81083171ec13ea4f122f9c2bc7a68378de55fb0e61631266ae3cc2e94' 
  AND token = 'M7jwRk8sK9Ch992/mLRIN6c7iWU9shhTWyjLVdFzHuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}