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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72afa8415aae09b5b3fb24a5f5d31f3342c8176c7c45a5e979d5c73904d5b4a6' 
  AND token = 'aPZ85KNMZujw3S/V2FuHSOdg5PudjQuHlvNTjFUbxuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}