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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b61b0eb25fdfd9a28d1a542b0cc5046c72db1caebd6c13802b63820ec04a34e8' 
  AND token = 'oyD40aq/4dOg5sl6FHeEu+sx02PpNE93314ZPMNjAyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}