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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80caed1f2d920cec7c8982116770e581bdc42c8a292cb5e59781ca3f1d73f320' 
  AND token = 'LEWsfH6stazDJwL/iUbNZecUpoA7f9SV7vWOVF2JF+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}