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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'accbe66ef77277ebafc0c53eb0bb24aaca6275f3c0990d3ad54c52e8b6d75f25' 
  AND token = 'y3R5mBS+R4kclGsUWzMCqhoCuEWIngNTrRuFrxCh6W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}