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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b10c198d926a1fa8711dde622206da2287dac9ec185e291994be2ea252561ca' 
  AND token = 'cz+SSBx0C66dOTQliBEZSl3G6BFpXbEJyFt+iX2EmQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}