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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8126d2aedd0aa34d832f237fbbfb6ed58cb13c27254d88fa99d2400cebe8fd1' 
  AND token = 'bkjH6PikgpQ0B0IQ95s5TP0cXyrU8D6fF+I6BO3kdsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}