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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e6d50a80377fc62662f8d1017462c5851175c762445bd10ddba9d182a851b3' 
  AND token = 'I1Lj2nkgGS7Hv9sbHhscaJ+NQaZv3+2p+xFzfRdFy1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}