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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5d4a7c693877ba5dbc04cdb808647b547ce1ce7a7f97cb3abad18d655f2b591' 
  AND token = 'At5bBLuPTVHzRKWzC53y/2zgQ8/5PNH5R6kgQkhbq9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}