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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45dcc1635b4b799f15d7ac532b3d6a3a8c9596d78c7cc5341644c0a7c86c79f' 
  AND token = '6v2GiXaJX/Woit6dXuMIQUUqkDLTRQwPkyo5ASdPIwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}