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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5caafed880f73bc6242a686162aae4132d5b84d33a4397aa2522b5320a1237b7' 
  AND token = 'VO1uRF1ipVyicWnHFPHfg9cp3YbqQqmB/AG8q7YhAPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}