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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf5cda742ec7f4630e08b8d33b4a287c5730a3af16f3b3d2e906910ec3553c4f' 
  AND token = 'earw27uNgyj7O0bLbOUMmFY2LNRzrbLYZfe2bO0cYlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}