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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c0506be2a5630bfb4a027a5d34d219bf6c9759198145f2b6f35e9a4777e7bb' 
  AND token = 'BG4O6DWSmFxxBp70SdWGn5JANyTLLIwVGenUrId/65Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}