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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0974a4020f250a52085e05ad3b525cb830dd72a3dd2c40a75f53feeec74cd3' 
  AND token = 'U6LcJXrEF8vRqsIxS7W97AVEvebUsW3FWZn6pjRauRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}