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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5c005aff7aad8ebe80704155909cc09e0783426234b6773df2ef511791e6af' 
  AND token = 'wrvUb+dcHklzfYyb44uwD5m1Cdjk1vFGWzCb0lNytxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}