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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6035c941ef09cacba9191774ef837a5f5a07d950c2543b085c079c64b18e1455' 
  AND token = 'BtTDrCLr/lCTfr1EDTgSbC6MAhrr1f4Y19eg2XqrTfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}