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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0bb5a43d5655ec0c17d6c01a6715f0dcf00570ef1cc25dddeeec5572406822' 
  AND token = 'QV3r+MZDGpbr/ar/AfmcG+pPxdA9/Fe99dx9rNJqCJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}