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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2218ebd25172078caab18dc9fc9e3d0ac6d9b8a88620e425927d0922551418c0' 
  AND token = 'ffIdi55Ui/ZlR0YfhGliRZ3EPZrDXf2pKJxVf3XquLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}