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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e5c264c1481b65cd32466132d326f2e20a03403e897e09066f5cbb4940b481' 
  AND token = '3UtKTB3FM7qkqNUHkaTKOH7rCtlVvEF2yJz+Bs43dYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}