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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f2dd3ae612df534f92eff1ec405077aab71aeaf949643b40c36f904b6eeaa4' 
  AND token = '4SkcGh0paLbC7CWDRN2ZJrDVVpNhwxSh9c72j6B1Xiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}