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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4fa7cd46a344c65f1e1b28c2f594b5603c1e901f54521fe695b9cda77cbdfc' 
  AND token = 'k41nWZ8Qpv41XzSlMLHYBW/fdXpKbw3MW2v9qcLwvqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}