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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3d2ccea12a36d9d22547765e658ed5326ed72f7d69deaed5290b8fa2e0447b1' 
  AND token = 'M+CrnM32yRPu0uMXsjB6TCjaIvbU7caPEKwDcUfxi18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}