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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db8da6f946e1da256a8dcd3886e22e99815680b4bc5a16d44235ace580c0d642' 
  AND token = 'ZfXMA7oarh0DHUucIZdTZK2QVtD4WdSVeglG8l0z+98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}