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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d196099664bd10f4eab58a48efeffec64e72b81e8422e0bd1daabe550a3bda0' 
  AND token = 'mekuJuwtLOT/MntMa/Zj75DW+0dwvoWzTLQwlEclBMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}