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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0b28dce75810124dfa01760561223fabaad7d0e64f879739e9415cc8da8b734' 
  AND token = 'zfuPevebX90JJB4maVujb46iiHq5AewyNpbxJKE4JYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}