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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5141b151aeb7b1d5a304c33bd04d6345e17647230ff442063a203416cd2c7f8a' 
  AND token = 'P547yXH2SLWLeI63jtz/koDA7swh42METk2B4HifjCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}