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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a26f5c7eb834d66e86dfcaa1762d7c34c36976d722cbeeba57f66329ff363109' 
  AND token = 'RUSZUv0tROc5Va6qf/91tPUl3NOveCogs4Avc3V1BOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}