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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257e75a9297e29d5a02518e9f12fe7e209d30dda45245d8ab964a04fe5f2275d' 
  AND token = 'Zec2QpnwD3pwywClFjelxU0FNwTCh/1fKkHg35gq+fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}