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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d49d90c572b6fa90f9e5866f7aee17c4bdf25a81d88290884c47edcee66dfc9' 
  AND token = 'JL/U3KZgraHA09hdozzh8thn/kbcZlcy9S9zdTEm+Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}