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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eceaf70d085e97dce70712f84c1ab223b75216163e2e0c4747d2d55d3f67987' 
  AND token = '+u4Y4RrB4tQu1r4WVaTwL+Vht/JgWFlbO5p2cIU+1F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}