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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09424f371206ebf27c5729c8960069d9aebbdcda8c607d74e0ef8e0f4930e0d9' 
  AND token = 'AoO7zi5G1NIFoBm/OB6wYMdDHASgXxMQl2ZeS/uoRQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}