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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a40e243acfb9916023541ffb2462d9206804d0774a82f5f3a289b0cc9ca71a' 
  AND token = 'fxaBI7cyBqXW6y8sygLYbUho41bOwtH1Bj3pluEKdx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}