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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc348cb95de7085684aa7da9415ea9d07c9a06b31eb692ec6701ac355f9d3eff' 
  AND token = '20OqkdE+GfHwCs/Fzk6jWLPiZUMh1eQDOL9z6X8Cry0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}