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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5039d3d5363ec1f2d11095cd32e5388bd1a002d83357dcc13cf0333ab630afa3' 
  AND token = 'CGECSeMq+3cXxu6Zf3vAno6HVJruAKwL9TqB79LrEiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}