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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac48558195bc8feb2edd3c4290a8478dac96d9074a33956e86350ad152a3e263' 
  AND token = 'o6O2MQC/6kYbKVoOcP4cI7joLrxJtuU3N8cO+d3ELNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}