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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b74399bf325bb672627eada39e35ba92bb57d05ec9bb5bd39dc147ec606df55' 
  AND token = 'My62AexbchVx/ZxdNS5dHB5haqGt+l751uBCCBiPHUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}