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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0714d945d9659b78da6c5eec4dd5846a7db8794eacfc86e1e068e72e4f343d' 
  AND token = 'A6oaO+ER0dsmh/U6HiIvsG83OQgBYjlonrxJ9b5JzWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}