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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3bcb972f67098174e791738865e1fbbf8e00c1be93d78a92ef43fefb8954f98' 
  AND token = '/yJ//I/Czh+Pf1PKpeO+09JRwsWlwPW2z66/LOQ88Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}