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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8ed0eb28a685e6f0658b7a36e9832d4445117abee334d4551c6d22f0f0b56a' 
  AND token = '+6YkhhmrXeDIkCqO2VaNApWzFJUBUCtCcQacPTm62Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}