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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251e98e031fb1720b8bffb9afd8086c8d9bb11893eef7ff338ab51f108e9713a' 
  AND token = 'vFp46+/aMfzQekhmggY/E3bU/uc1mB5wjO88e9qcbNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}