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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d46b657f842d0818145fed543775b003104a4388ca4f2d95ce25cc265bde9e' 
  AND token = '+Z3xnmQMsQaMXxHgW1Q/xE//+TLpkR9N8ZpKzxDHUlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}