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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a0189e6f0ef9648dcca941ea2206ccc773a2c49d1ee2f7deaccee58ad786a0' 
  AND token = 'TVZWyXQB5lhcf6fUlRQ2ioH49ytsZxoJAfLTfyVzAZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}