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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d5704c731927f589d6fad3c23f064d5d64b70520fc5fc272fd8261878a4943' 
  AND token = 'U/puqgrXXXs4GrEo8zSNk6J1QW4Bgn0n5SCntyhB5Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}