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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87a45d989dc2a80dee6a93c361cd685c8ec9efabfc81055ef2d15f43530b00e8' 
  AND token = 'P6Q6XzeljO3+VIjJY6/WSe3zCn+1oCSPAJTRTLok6G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}