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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8865327ff01b17a40c5b1778459cdfa56645619a93c598dfebaabe14c14b4fb6' 
  AND token = 'q1866yPq9SFvOWWXPV1XxBaWK1BfAUyCzA3nzXX+VSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}